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Twenty-eight years since the rage virus escaped a biological weapons laboratory, now, still in a ruthlessly enforced quarantine, some have found ways to exist amidst the infected. One such group lives on a small island connected to the mainland by a single, heavily-defended causeway. When one member departs on a mission into the dark heart of the mainland, he discovers secrets, wonders, and horrors that have mutated not only the infected but other survivors as well.

An American pulp writer arrives in Vienna only to find that the friend who waited for him is killed under mysterious circumstances. The ensuing mystery entangles him in his friend's involvement in the black market, with the multinational police, and with his Czech girlfriend.